国家卫健委小儿先天畸形重点实验室

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近期发表代表性论著

1. Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z. Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation. J Med Genet. 2023 Apr 3:jmg-2022-108888. IF=5.941，1区

2. Huang W, Fu J, Yuan Z, Gu H. Impact of prenatal exposure to metallic elements on neural tube defects: Insights from human investigations. Ecotoxicol Environ Saf. 2023 Mar 20;255:114815. IF=7.129，1区

3. Wei X, Ma W, Gu H, Liu D, Luo W, Cao S, Jia S, Huang T, He Y, Bai Y, Wang W, Yuan Z. Intra-amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses. Cell Prolif. 2023 Feb;e13354. IF=8.755，1区

4. Chen L, Xiu Y, Wu Q, Wang Y, Zhang Y, Xue J, Wang Q, Yuan Z. Maternal serum Lamin A is a potential biomarker that can predict adverse pregnancy outcomes. EBioMedicine. 2022 Mar;77:103932. IF=11.205，1区

5. Zhao D, Liu Y, Jia S, He Y, Wei X, Liu D, Ma W, Luo W, Gu H, Yuan Z. Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring. Biomed Pharmacother. 2022 Jul;151:113103. IF=7.419，1区

6. Li SY, Wang CY, Wei XG, Tang XB, Yuan ZW, Bai YZ. CircJag1 promotes apoptosis of ethylene thiourea-exposed anorectal malformations through sponging miR-137-3p by regulating Sox9 and suppressing Wnt/β-catenin pathway during the hindgut development of rat embryos. Cell Biol Toxicol. 2022 Aug 5. doi: 10.1007/s10565-022-09750-0. Epub ahead of print. IF=6.819，1区

7. Liu P, Li Y, Wang W, Bai Y, Jia H, Yuan Z, Yang Z. Role and mechanisms of the NF-ĸB signaling pathway in various developmental processes. Biomed Pharmacother. 2022 Sep;153:113513. IF=7.419，1区

8. Zhou W, Luo W, Liu D, Canavese F, Li L, Zhao Q. Fluoride increases the susceptibility of developmental dysplasia of the hip via increasing capsular laxity triggered by cell apoptosis and oxidative stress in vivo and in vitro. Ecotoxicol Environ Saf. 2022 Mar 14;234:113408. IF=7.129，1区

9. Huang W, Huang T, Liu Y, Fu J, Wei X, Liu D, Ma W, Gu H, Yuan Z. Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects. Cell Death Dis. Cell Death Dis. 2021 Dec 20;13(1):17. IF=9.696，1区

10. Jia S, Zhang Q, Wang Y, Wang Y, Liu D, He Y, Wei X, Gu H, Ma W, Luo W, Yuan Z. PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate. EBioMedicine. 2021 Feb 24;65:103253. IF=8.143，1区

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